Clinical Practice And Studies

The National Institute of Health has funded studies of Noni Juice (morinda citrifolia) since the 1950's at the Univerity of Hawaii. The Cancer Research Center in Hawaii is currently in Phase II of it's clinical trials using Noni as a cancer treatment. Noni is still used by the local population in Hawaii for sugar control diseases, high vascular pressure, heart health maintenance, abnormal growths, and other chronic disorders, although no controlled clinical studies exist to support these uses. Based on clinical practice and animal studies, a polysaccharide-rich substance from noni fruit juice attacks abnormal cells in several different ways.  

Potent Antioxidant Activity

Noni juice also has potent antioxidant activity. Researchers conclude that noni juice could be used in clinical applications as a supplemental agent to reduce side-effects and improve chemotherapy. In animal studies, noni juice treatments prolonged the life span of mice by more than 75%.

Noni Fruit Contains:

The active ingredients are polysaccharides found in a polysaccharide-rich substance in the water-soluble fraction of the fruit juice. A novel trisaccharide fatty acid ester was recently identified from the fruits of noni. The fruit also contains the plant acids, hexoic acid and octoic acid, and paraffin.

Ubiquitous Substances

The potassium concentration in noni juice samples was determined and found to be 56.3 mEq/L. Other ubiquitous substances are also found in the fruit. Several noni products are marketed with the information that the key active ingredients in noni are alkaloids called proxeroxine and proeronase. These compounds have yet to be identified by conventional researchers and have not been reported in peer-reviewed scientific publications; it appears that the claims may be false.

Low-Potassium Diet

Noni juice, as a rich source of potassium, is contraindicated in cases of chronic renal insufficiency. There is a case report on noni juice involving a man with chronic renal insufficiency that self-medicated with noni juice and presented to a clinic with hyperkalemia despite claiming adherence to a low-potassium diet. People that cannot eat bananas (due to its potassium content), should probably not consumer noni fruit or juice as well.

Health-Related Ingredients

Noni is receiving more and more attention from modern herbalists, medical physicians, and high-tech biochemists. Scientific studies within the last few decades lend support to the Polynesians' claims of its unusual healing power. Some of the health-related ingredients of Noni fruit that have been isolated are Morindone, Morindine, Acubin, Terpene compounds, L. Asperuloside, various Anthraquinones, Alazarin, Caproic Acid, Caprylic Acid, Scopoletin, Damnacanthal, and Alkaloids.

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